GDV FOR FOR SALT-SENSITIVE HYPERTENSION
ELECTROPHOTONIC IMAGING AS A NONIVASIVE DIAGNOSTIC DEVICE FOR SALT-SENSITIVE HYPERTENSION:
A PROSEPCTIVE STUDY PROPOSAL
Brennan Carrithers, M.S. – Biophotomics, LLC – brennan.carrithers@gmail.com
Hypertension ultimately leads to chronic illnesses such as cardiovascular disease, renal disease, liver fibrosis, and exacerbates neurological or autoimmune conditions.
The mainstay of monitoring one’s blood pressure (Korotkov’s sounds) is the blood pressure cuff; however, this device is highly unreliable and does not provide any information about the pathophysiology of processes that lead to a patient’s persistent high blood pressure.
From a preventative medical perspective, solving this widespread issue will require the identification of at-risk individuals, establishing and monitoring an action plan, and routinely providing them with essential information about their overall health.
Electrophotonic Imaging (EPI) allows for non-invasive self-monitoring with a simple fingerprint scan that can be correlated to a person’s overall health and to pathophysiologic processes that may influence the early development of hypertension.
For this proposed effort, we will evaluate the performance of EPI in prospective clinical trials and samples from retrospective clinical trials, such as the DASH-Sodium Trial. In correlating the detailed clinical and metabolic information from each subject, we will demonstrate an ability to discriminate between healthy and clinically-defined hypertensive patients.
The ultimate goal of this project so that we can obtain FDA approval for the commercialization of an EPI device that will
(1) monitor the health of healthy subjects;
(2) detect the onset of hypertension and characterize severity in hypertensive patients (especially those resistant to mainstay medications);
(3) reflect early pathophysiology related to the risk of potential chronic diseases sequelae of hypertension; and
(4) be used for real time monitoring of regression / progression of hypertension and the effectiveness of medical intervention.